• NCS is a rare syndrome In

  2019-05-22

  

  NCS is a rare syndrome. In case series of NCS 14–47% were associated with of lymphoproliferative disorders [reviewed in [12]]. Survival is usually dictated by the underlying disease and short in the setting of aggressive malignancies. Since NCS may be a manifestation of an underlying malignancy it h

• years ago published a groundbreaking and taboo breaking Seri

  2019-05-22

  

  5 years ago, published a groundbreaking (and taboo-breaking) Series on stillbirths. Its powerful mix of advocacy and hard data attracted more media attention than perhaps any other Series, and made waves on numerous levels, from the individual to the intergovernmental. Working closely with countrie

• br Material and methods br Results br Discussion

  2019-05-22

  

  Material and methods Results Discussion ES-SCLC is a disease with poor prognosis. Treatment outcome has not improved significantly during the last decades despite great efforts have been made. Maintenance therapy has been tried in several clinical trials with the aim to prevent the onset of

• Lymphocytic infiltrates in thyroid cancer may suggest

  2019-05-22

  

  Lymphocytic infiltrates in thyroid cancer may suggest a background of chronic lymphocytic thyroiditis. Thyroiditis is characterized by a cellular immune response with dense lymphocytic infiltration of the thyroid gland, as well as by a humoral immune response leading to the production of autoantibod

• In addition to inducing IKs dysfunction through dominant neg

  2019-05-22

  

  In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor

• A type saddle back type or type ST segment

  2019-05-22

  

  A type 2 (“saddle-back type”) or type 3 ST-segment elevation cannot substitute for a type 1, unless converted to type 1 with fever or sodium drug challenge. A drug challenge–induced type 1 can be used to diagnose BrS only if accompanied by 1 of the criteria specified above. Type 2 is characterized b

• Initial bone marrow biopsy was inadequate in size

  2019-05-21

  

  Initial bone marrow biopsy was inadequate in size for detailed examination and had severe crush artifact. The preserved focus of marrow showed hypercellularity with large, multinucleated, dysplastic megakaryocytes and megaloblastoid changes in erythroid series (Fig. 1B and C). There was no increase

• All statistical analyses were performed using SPSS software

  2019-05-21

  

  All statistical analyses were performed using SPSS software (version 15; SPSS Inc., Chicago, IL, USA). Continuous data are expressed as mean (standard deviation) and were analyzed with two independent-samples tests. Chi-square and Fisher\'s exact tests were used for categorical data. The significanc

• br The L type calcium channel LTCC in heart

  2019-05-21

  

  The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot

• In the current era nearly

  2019-05-21

  

  In the current era, nearly all cases of hormone-receptor positive breast cancer are treated with adjuvant endocrine therapy irrespective of staging, with preference for aromatase inhibitors over tamoxifen because of side effect profile, survival outcome and tumor recurrence rates [4,11]. In our stud

• El trasfondo musical de la obra de sor Juana

  2019-05-21

  

  El trasfondo musical de la obra de sor Juana Inés de la Cruz ha recibido la atención de connotados críticos, tanto del ámbito de la música como del de las letras. Quien parece haber inaugurado en toda forma esta veta crítica es Alfonso Méndez Plancarte en su admirable anotación de la obra de sor Jua

• br In this issue of Tiffany

  2019-05-21

  

  In this issue of , Tiffany Chao and colleagues present a systematic, comprehensive, and critical assessment of published estimates of the cost-effectiveness of essential surgery, and thus make an important contribution to the published work on the economics of global health interventions. Their he

• br Comments The present two cases developed ACC during

  2019-05-21

  

  Comments The present two cases developed ACC during chemotherapy induced neutropenic for AML. ACC is a relatively rare complication in these patients’ population. It’s reported in 0.4% among all neutropenic episodes of patients with acute leukemia or aggressive lymphoma undergoing myelosuppressiv

• To facilitate WHO s goals

  2019-05-21

  

  To facilitate WHO\'s goals, it folate analogue is important to assess the cost-effectiveness of interventions that incorporate emerging technologies for case detection, treatment, and vector control in the context of economic constraints and logistical barriers. In an elegant modelling study in , S

• The distribution of dental treatments and the number

  2019-05-21

  

  The distribution of dental treatments and the number of treated teeth within each age group were also analyzed. The  6-years-old group had the lowest mean number of teeth treated by stainless-steel crown (SSC) and the lowest number undergoing pulp therapy (porder 3X FLAG and, when compared against

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