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An important feature of stem cells is
2018-10-29

An important feature of stem opioid receptor is their ability to grow indefinitely in culture; hence, to shed light on this issue, cell doublings were monitored over time. The NPCs were capable of more than 60 population doublings without ceasing to proliferate, although an initially high prolifera
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Using our screening we were able to confirm the previously
2018-10-29

Using our screening, we were able to confirm the previously determined cytogenetic karyotypes of 34 mESC lines and to further validate our method using 19 additional mESC lines with unknown cytogenetic karyotypes. Our study includes the screening of five mESC lines that produced germline transmissio
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Although the CAG expansion in ATXN
2018-10-26

Although the CAG-expansion in ATXN3 is known to cause SCA3, the underlying cellular mechanisms leading to neurodegeneration are not fully elucidated. It has been proposed that the polyQ expansion alters normal ataxin-3 functions in for example endoplasmic reticulum associated degradation (ERAD) and
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In recent promising studies various stem cell types have
2018-10-26

In recent promising studies, various stem cell types have been used as an alternative source for BBB remodeling. Stem cells are self-renewable, can be subsequently differentiated into mature somatic cell types, and serve as a virtually unlimited independent cell source. In particular, hematopoietic
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In summary we report the robust differentiation
2018-10-26

In summary, we report the robust differentiation and subsequent transplantation of mESC-derived cone precursors (summarized in Figure S7). Cones differentiated in vitro following a specification sequence resembling that observed in vivo, indicating that mESC-derived retinal organoids represent a dev
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metabotropic glutamate receptor br Methods A scoping review
2018-10-26

Methods A scoping review determines the extent, range and nature of any research activity, making it a more suitable approach than a systematic review for this research question (Arksey & O’Malley, 2005; Levac, Colquhoun, & O’Brien, 2010). Given the complexity of the review design, a detailed pro
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In this paper we show that
2018-10-26

In this paper, we show that prisoners report worse health than their noninstitutionalized counterparts. Incarceration is associated with a higher prevalence of hypertension, diabetes, heart problems, asthma, kidney problems, stroke, arthritis, and STI, with differences larger for whites than blacks,
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Aside from differences between countries differences also ex
2018-10-26

Aside from differences between countries, differences also exist within countries. Indeed, recent research shows that in many African countries attitudes related to female genital cutting vary substantially at the individual and household levels (Bellemare et al., 2015; Efferson et al., 2015; Hernlu
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The type of occupation of an individual may
2018-10-26

The type of occupation of an individual may influence the place of death. We found that Forskolin cost most of the adult deaths occurred among those with elementary occupations, closely followed by those in agricultural and fishery occupations. However, with the exception of the skilled agricultural
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To support claims of benefit in terms of reduced environment
2018-10-26

To support claims of benefit, in terms of reduced environmental burden or increased process sustainability, rigorous process analysis is required using tools such as Life Cycle Assessment or carbon- and water footprinting. These approaches require availability of material and trpv1 inventories, as
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br Acknowledgement br Introduction The
2018-10-26

Acknowledgement Introduction The world is currently challenged with global warming, depletion of non-renewable fossil fuel and environmental pollution. The major sources of greenhouse gas emissions are fossil fuels (Endalew et al., 2011). To overcome these challenges, there is a need to find a
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Risk behaviours are important threats during adolescence due
2018-10-26

Risk behaviours are important threats during adolescence due to possible lifetime negative consequences. Their prevalence is high in the USA: the percentage of those who ever smoke, drunk, use marijuana and cocaine was respectively 44.7, 70.6, 39.9 and 18.2% in a national survey; the percentages of
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Although sleep duration was not related
2018-10-26

Although sleep duration was not related to morningness-eveningness, many other sleep-related aspects were different in students with different circadian preferences. In line with previous work [3,7,13–15] and our hypotheses, eveningness in our results was related to daytime tiredness/sleepiness. Fur
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br Methods br Results br Discussion In this study
2018-10-26

Methods Results Discussion In this study, a prevalence value for daytime sleepiness and sleep complaints in airline pilots was established. Regarding fatigue, a high prevalence for this professional group was also observed. The variable ‘type of flight’ had a statistically significant predi
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br Experimental br Result and discussions br Integration of
2018-10-26

Experimental Result and discussions Integration of the FIA-ET biosensor with android platform Facilitation of decision support system Decision support system is provided for data analysis. Android application is pre-programmed for decision making. Where necessary, computations are made w
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